The intrinsic defects of T cells impact the efficacy of CAR-T therapy in patients with diffuse large B-cell lymphoma

Abstract CAR-T cell therapy did not achieve the desired efficacy in some patients with diffuse large B-cell lymphoma (DLBCL). We conducted single-cell RNA and TCR sequencing as well as methylation chip profiling of peripheral blood samples in DLBCL patients. Patients who achieved complete remission...

Cijeli opis

Bibliografski detalji

Glavni autori:	Jinrong Zhao, Chong Wei, Shuqing Wang, Yan Zhang, Wei Wang, Danqing Zhao, Zi Wang, Zhipeng Zhou, Jing Bai, Wei Zhang, Daobin Zhou
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Publishing Group 2023-12-01
Serija:	Blood Cancer Journal
Online pristup:	https://doi.org/10.1038/s41408-023-00958-9
Oznake:	Dodaj oznaku Bez oznaka, Budi prvi tko označuje ovaj zapis!