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Diallyl trisulfide improves spinal cord ischemia–reperfusion injury damage by activating AMPK to stabilize mitochondrial function

Abstract Background Spinal cord ischemia–reperfusion injury (SCII) is a catastrophic event, which can cause paraplegia in severe cases. In the reperfusion stage, oxidative stress was up-regulated, which aggravated the injury and apoptosis of neurons. As the main active ingredient of garlic, diallyl...

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Principais autores: Yang Sun, Dengyue Xu, Weidong Yang, Hongquan Zhang, Yi Su, Bin Gao, Xiaowei Zou, Yiming Zhong, Huanwei Sun, Liangbi Xiang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-11-01
Serier:Journal of Orthopaedic Surgery and Research
Fag:
Spinal cord ischemia–reperfusion injury
Diallyl trisulfide
Mitochondrial function
Adenosine monophosphate activated protein kinase
Compound C
Online adgang:https://doi.org/10.1186/s13018-023-04176-8
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