PRMT6 Epigenetically Drives Metabolic Switch from Fatty Acid Oxidation toward Glycolysis and Promotes Osteoclast Differentiation During Osteoporosis

Abstract Epigenetic regulation of metabolism profoundly influences cell fate commitment. During osteoclast differentiation, the activation of RANK signaling is accompanied by metabolic reprogramming, but the epigenetic mechanisms by which RANK signaling induces this reprogramming remain elusive. By...

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Autors principals:	Wenxiang Chu, Weilin Peng, Yingying Lu, Yishan Liu, Qisheng Li, Haibin Wang, Liang Wang, Bangke Zhang, Zhixiao Liu, Lin Han, Hongdao Ma, Haisong Yang, Chaofeng Han, Xuhua Lu
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2024-10-01
Col·lecció:	Advanced Science
Matèries:	fatty acids oxidation glycolysis metabolic reprogramming osteoclastogenesis PRMT6
Accés en línia:	https://doi.org/10.1002/advs.202403177
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