Single-cell profiling of Anopheles gambiae spermatogenesis defines the onset of meiotic silencing and premeiotic overexpression of the X chromosome

Abstract Understanding development and genetic regulation in the Anopheles gambiae germline is essential to engineer effective genetic control strategies targeting this malaria mosquito vector. These include targeting the germline to induce sterility or using regulatory sequences to drive transgene...

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Hlavní autoři:	Nicole Page, Chrysanthi Taxiarchi, Daniel Tonge, Jasmina Kuburic, Emily Chesters, Antonios Kriezis, Kyros Kyrou, Laurence Game, Tony Nolan, Roberto Galizi
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2023-08-01
Edice:	Communications Biology
On-line přístup:	https://doi.org/10.1038/s42003-023-05224-z
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