A Genome-Wide CRISPR/Cas9 Screen Reveals the Requirement of Host Sphingomyelin Synthase 1 for Infection with Pseudorabies Virus Mutant gD^–Pass

Herpesviruses are large DNA viruses, which encode up to 300 different proteins including enzymes enabling efficient replication. Nevertheless, they depend on a multitude of host cell proteins for successful propagation. To uncover cellular host factors important for replication of pseudorabies virus...

Fuld beskrivelse

Bibliografiske detaljer

Principais autores:	Julia E. Hölper, Finn Grey, John Kenneth Baillie, Tim Regan, Nicholas J. Parkinson, Dirk Höper, Thiprampai Thamamongood, Martin Schwemmle, Katrin Pannhorst, Lisa Wendt, Thomas C. Mettenleiter, Barbara G. Klupp
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2021-08-01
Serier:	Viruses
Fag:	herpesvirus pseudorabies virus PrV gD<sup>–</sup>Pass CRISPR/Cas9 gene editing sphingomyelin synthase
Online adgang:	https://www.mdpi.com/1999-4915/13/8/1574
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!