QR-Code

Mice with altered serotonin 2C receptor RNA editing display characteristics of Prader–Willi syndrome

RNA transcripts encoding the 2C-subtype of serotonin (5HT2C) receptor undergo up to five adenosine-to-inosine editing events to encode twenty-four protein isoforms. To examine the effects of altered 5HT2C editing in vivo, we generated mutant mice solely expressing the fully-edited (VGV) isoform of t...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Michael V. Morabito, Atheir I. Abbas, Jennifer L. Hood, Robert A. Kesterson, Michelle M. Jacobs, David S. Kump, David L. Hachey, Bryan L. Roth, Ronald B. Emeson
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2010-08-01
Schriftenreihe:Neurobiology of Disease
Schlagworte:
RNA Editing
Serotonin receptor
Prader–Willi syndrome
Feeding behavior
Metabolism
Hyperphagia
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S0969996110001014
Tags: Tag hinzufügen
Keine Tags, Fügen Sie das erste Tag hinzu!

Ähnliche Einträge