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Trimethylamine N-oxide aggravates vascular permeability and endothelial cell dysfunction under diabetic condition: in vitro and in vivo study

AIM: To provide the direct evidence for the crucial role of trimethylamine N-oxide (TMAO) in vascular permeability and endothelial cell dysfunction under diabetic condition. METHODS: The role of TMAO on the in vitro biological effect of human retinal microvascular endothelial cells (HRMEC) under hig...

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Principais autores: Jia-Yi Jiang, Wei-Ming Liu, Qiu-Ping Zhang, Hang Ren, Qing-Ying Yao, Gao-Qin Liu, Pei-Rong Lu
Formato: Artigo
Idioma:Inglês
Publicado em: Press of International Journal of Ophthalmology (IJO PRESS) 2024-01-01
coleção:International Journal of Ophthalmology
Assuntos:
diabetic model
trimethylamine n-oxide
inflammation
endothelial dysfunction
rats
retinal microvascular endothelial cells
Acesso em linha:http://ies.ijo.cn/en_publish/2024/1/20240104.pdf
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