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Intraoperative Low-Dose Methadone for Pediatric Posterior Spinal Fusion: A Single-Center Retrospective Cohort Study

<b>Background:</b> Posterior spinal fusion (PSF) for adolescent idiopathic scoliosis causes significant postoperative pain and high opioid requirements. Methadone, with dual μ- and κ-opioid agonism and NMDA antagonism, provides long-acting analgesia and may reduce perioperative opioid use. This stud...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Roshni Cheema, Kristina Boyd, Mihaela Visoiu, Hsing-Hua Sylvia Lin, Scott E. Licata, Ruth Ressler, Vishali Veeramreddy, Shraddha Sriram, Selena Rashid, Senthilkumar Sadhasivam, Paul Hoffmann
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2026-03-01
Schriftenreihe:Children
Schlagworte:
posterior spinal fusion
methadone
postoperative analgesia
opioid consumption
adolescent idiopathic scoliosis
pediatric
Online-Zugang:https://www.mdpi.com/2227-9067/13/3/400
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