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Upregulation of long intergenic non-coding RNA LINC00326 inhibits non-small cell lung carcinoma progression by blocking Wnt/β-catenin pathway through modulating the miR-657/dickkopf WNT signaling pathway inhibitor 2 axis

Abstract Background Long intergenic non-coding RNA 326 (LINC00326) modulates hepatocarcinogenic lipid metabolism. However, the ability of LINC00326 to modulate the highly aggressive non-small cell lung carcinoma (NSCLC) is unknown. Here, LINC00326 in NSCLC was investigated, together with its effects...

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Main Authors: Yingqian Zhang, Jiao Yuan, Mengfei Guo, Run Xiang, Tianpeng Xie, Xiang Zhuang, Wei Dai, Qiang Li, Qi Lai
Format: Artigo
Language:Inglês
Published: BMC 2023-02-01
Series:Biology Direct
Subjects:
LINC00326
NSCLC
miR-657
DKK2
Wnt/β-catenin pathway
Online Access:https://doi.org/10.1186/s13062-023-00359-9
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