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Synthesis, Biological Evaluation, and Computational Studies of Phenolic <i>N</i>-Acetylglucosamine Glycosides as α-Glucosidase Inhibitors

Type 2 diabetes mellitus (T2DM) is one of the most prevalent chronic metabolic diseases, and inhibition of α-glucosidase activity represents an effective therapeutic strategy. Chitin is the most abundant renewable polysaccharide in the ocean, with its monosaccharide being <i>N</i>-acetylglucosamine...

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Principais autores: Wenjie Wang, Kun Gao, Guantian Li, Zongji Wang, Kecheng Li, Song Liu, Huahua Yu, Ronge Xing
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2026-02-01
coleção:Marine Drugs
Assuntos:
α-glucosidase inhibitor
<i>N</i>-acetylglucosamine glycoside
phenols
DFT
molecular dynamic
diabetes
Acesso em linha:https://www.mdpi.com/1660-3397/24/2/84
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