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Sparstolonin B nano-formulation attenuates LPS-induced lung injury

IntroductionNanomedicines can improve drug delivery and efficacy while reducing side effects. Our study examines the impact of a nano-formulation of Sparstolonin B (nSsnB), a TLR-4 antagonist, on LPS-induced inflammation in RAW264.7 cells and lung injury in mice.MethodsRAW264.7 cells were treated wi...

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主要な著者: Qinghe Meng, Xiaojing Wang, Dandan Guo, Gary Zhang, Changying Shi, Adam Novak, Xiguang Yang, Juntao Luo, Robert N. Cooney
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2025-04-01
シリーズ:Frontiers in Pharmacology
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オンライン・アクセス:https://www.frontiersin.org/articles/10.3389/fphar.2025.1532391/full
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