Monosodium Urate Crystals Activate the Inflammasome in Primary Progressive Multiple Sclerosis

Inflammasome-driven inflammation is postulated to play a role in multiple sclerosis (MS), but there is no direct evidence that the nod-like receptor protein 3 (NLRP3) inflammasome is involved in MS pathogenesis. Uric acid was shown to be one of the “danger” signals involved in the activation of NLRP...

Полное описание

Библиографические подробности

Главные авторы:	Federica Piancone, Marina Saresella, Ivana Marventano, Francesca La Rosa, Maria Antonia Santangelo, Domenico Caputo, Laura Mendozzi, Marco Rovaris, Mario Clerici
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2018-05-01
Серии:	Frontiers in Immunology
Предметы:	multiple sclerosis inflammasome uric acid neuroinflammation immunity
Online-ссылка:	http://journal.frontiersin.org/article/10.3389/fimmu.2018.00983/full
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!