Comparative 3D genome analysis between neural retina and retinal pigment epithelium reveals differential cis-regulatory interactions at retinal disease loci

Abstract Background Vision depends on the interplay between photoreceptor cells of the neural retina and the underlying retinal pigment epithelium (RPE). Most genes involved in inherited retinal diseases display specific spatiotemporal expression within these interconnected retinal components throug...

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主要な著者:	Eva D’haene, Víctor López-Soriano, Pedro Manuel Martínez-García, Soraya Kalayanamontri, Alfredo Dueñas Rey, Ana Sousa-Ortega, Silvia Naranjo, Stijn Van de Sompele, Lies Vantomme, Quinten Mahieu, Sarah Vergult, Ana Neto, José Luis Gómez-Skarmeta, Juan Ramón Martínez-Morales, Miriam Bauwens, Juan Jesús Tena, Elfride De Baere
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2024-05-01
シリーズ:	Genome Biology
主題:	3D genome structure Hi-C HiChIP UMI-4C Neural retina Retinal pigment epithelium (RPE)
オンライン･アクセス:	https://doi.org/10.1186/s13059-024-03250-6
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