Effect of Degeneration on Fluid-Solid Interaction within Intervertebral Disc under Cyclic Loading – A Meta-Model Analysis of Finite Element Simulations

The risk of low back pain resulted from cyclic loadings is greater than that resulted from prolonged static postures. Disc degeneration results in degradation of disc solid structures and decrease of water contents, which is caused by activation of matrix digestive enzymes. The mechanical responses...

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Autors principals:	Mohammad eNikkhoo, Kinda eKhalaf, Ya-Wen eKuo, Yu-Chun eHsu, Mohammad eHaghpanahi, Mohamad eParnianpour, Jaw-Lin eWang
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2015-01-01
Col·lecció:	Frontiers in Bioengineering and Biotechnology
Matèries:	Response Surface Methodology Poroelastic FE model Porcine intervertebral disc Fluid-Solid Interaction Artificial degeneration
Accés en línia:	http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00004/full
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