Alternative exon usage creates novel transcript variants of tumor suppressor SHREW-1 gene with differential tissue expression profile

Shrew-1, also called AJAP1, is a transmembrane protein associated with E-cadherin-mediated adherence junctions and a putative tumor suppressor. Apart from its interaction with β-catenin and involvement in E-cadherin internalization, little structure or function information exists. Here we explored s...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Petra A. B. Klemmt, Eduard Resch, Isabell Smyrek, Knut Engels, Ernst H. K. Stelzer, Anna Starzinski-Powitz
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	The Company of Biologists 2016-11-01
Цуврал:	Biology Open
Нөхцлүүд:	AJAP1 Mammary gland Lactation Splice variants Adherence junctions Tumor suppressor protein
Онлайн хандалт:	http://bio.biologists.org/content/5/11/1607
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!