DDB2 represses epithelial-to-mesenchymal transition and sensitizes pancreatic ductal adenocarcinoma cells to chemotherapy

IntroductionDamage specific DNA binding protein 2 (DDB2) is an UV-indiced DNA damage recognition factor and regulator of cancer development and progression. DDB2 has dual roles in several cancers, either as an oncogene or as a tumor suppressor gene, depending on cancer localization. Here, we investi...

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Detalhes bibliográficos

Principais autores:	Julie Dardare, Andréa Witz, Margaux Betz, Aurélie Francois, Morgane Meras, Laureline Lamy, Aurélien Lambert, Stéphanie Grandemange, Marie Husson, Marie Rouyer, Jessica Demange, Jean-Louis Merlin, Alexandre Harlé, Pauline Gilson
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-12-01
coleção:	Frontiers in Oncology
Assuntos:	damage specific DNA binding protein 2 pancreatic ductal adenocarcinoma epithelial-to-mesenchymal transition chemosensitivity biomarker prognosis
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fonc.2022.1052163/full
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