Rapid donor-specific single nucleotide variation detection by nanopore sequencing of ex vivo lung perfusate

Background: Donor-derived cell-free DNA (ddcfDNA) has been shown to be useful in monitoring lung graft health, and single nucleotide variations (SNVs) between donor and recipient are used to identify ddcfDNA in post-transplant recipient blood. One limitation is the need to map donor or recipient SNV...

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Principais autores:	Haruchika Yamamoto, Jonathan Allen, Adam Sundby, Philip Zuzarte, Shaf Keshavjee, Jared Simpson, Gavin W. Wilson, Jonathan C. Yeung, MD, PhD, FRCSC
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2026-02-01
叢編:	JHLT Open
主題:	Donor-derived cell free DNA Lung transplantation Ex vivo lung perfusion Molecular testing Nanopore sequencing
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2950133425002320
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