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Case Report: IL2RA (CD25) deficiency: first reported cases in Morocco

CD25, the α-chain of the interleukin-2 receptor (IL2RA), is a key component of the IL-2 pathway and is essential for the development and stability of regulatory T cells. Loss-of-function variants in IL2RA cause a very rare autosomal recessive disorder marked by early-onset autoimmunity and recurrent...

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Uloženo v:
Hlavní autoři: Ahamada Elamine, Ibtihal Benhsaien, Abderrahmane Errami, Yousra Bellarhrib, Zahra Aadam, Mohammed Fahi, Ahmed Aziz Bousfiha, Jalila El Bakkouri, Fatima Ailal
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2026-01-01
Edice:Frontiers in Immunology
Témata:
autoimmunity
CD25 deficiency
IL2RA deficiency
immune dysregulation
inborn errors of immunity
IPEX-like syndrome
On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1753561/full
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