Dynactin subunit p150(Glued) is a neuron-specific anti-catastrophe factor.
Regulation of microtubule dynamics in neurons is critical, as defects in the microtubule-based transport of axonal organelles lead to neurodegenerative disease. The microtubule motor cytoplasmic dynein and its partner complex dynactin drive retrograde transport from the distal axon. We have recently...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2013-07-01
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| Series: | PLoS Biology |
| Acceso en liña: | http://europepmc.org/articles/PMC3712912?pdf=render |
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