Evaluation of a Keratin 1 Targeting Peptide-Doxorubicin Conjugate in a Mouse Model of Triple-Negative Breast Cancer

Chemotherapy is the main treatment for triple-negative breast cancer (TNBC), a subtype of breast cancer that is aggressive with a poor prognosis. While chemotherapeutics are potent, these agents lack specificity and are equally toxic to cancer and nonmalignant cells and tissues. Targeted therapies f...

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Bibliografiske detaljer

Principais autores:	Azam Saghaeidehkordi, Shiuan Chen, Sun Yang, Kamaljit Kaur
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2021-05-01
Serier:	Pharmaceutics
Fag:	triple-negative breast cancer peptide-drug conjugate or peptide-doxorubicin conjugate keratin 1 targeting cell-derived xenograft antitumor efficacy off-target toxicity
Online adgang:	https://www.mdpi.com/1999-4923/13/5/661
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