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Exosomal Galectin-3 promotes peritoneal metastases in gastric adenocarcinoma via microenvironment alterations

Summary: Peritoneal carcinomatosis (PC) in gastric adenocarcinoma (GAC) is the most common metastatic site and leads to a short median survival. Exosomes have been shown to remodel the microenvironment, facilitating tumor metastases. However, the functional component in GAC cell-derived exosomes tha...

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Principais autores: Yibo Fan, Shumei Song, Melissa Pool Pizzi, Gengyi Zou, Jody V. Vykoukal, Katsuhiro Yoshimura, Jiankang Jin, George A. Calin, Rebecca E. Waters, Qiong Gan, Linghua Wang, Samir Hanash, Shilpa S. Dhar, Jaffer A. Ajani
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-01-01
Serier:iScience
Fag:
Microenvironment
Cell biology
Cancer
Online adgang:http://www.sciencedirect.com/science/article/pii/S2589004224027913
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