Nonsense‐mediated decay factor SMG7 sensitizes cells to TNFα‐induced apoptosis via CYLD tumor suppressor and the noncoding oncogene Pvt1

Nonsense‐mediated decay (NMD) proteins are responsible for the surveillance and degradation of aberrant RNAs. Suppressor with morphogenetic effect on genitalia 7 (SMG7) is an NMD complex protein and a regulator of tumor necrosis factor (TNF)‐induced extrinsic apoptosis; however, this unique function...

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Autori principali:	Limeng Yang, Vanessa A. N. Kraft, Susanne Pfeiffer, Juliane Merl‐Pham, Xuanwen Bao, Yu An, Stefanie M. Hauck, Joel A. Schick
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2020-10-01
Serie:	Molecular Oncology
Soggetti:	apoptosis cancer CYLD lncRNA nonsense‐mediated decay Smg7
Accesso online:	https://doi.org/10.1002/1878-0261.12754
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