Dynorphin activation of kappa opioid receptor promotes microglial polarization toward M2 phenotype via TLR4/NF-κB pathway
Abstract Background Microglia-mediated neuroinflammation is associated with epilepsy. Switching microglial polarization from the pro-inflammatory M1 phenotype to the anti-inflammatory M2 phenotype represents a novel therapeutic strategy for mitigating epileptogenesis. We previously found that dynorp...
שמור ב:
| Principais autores: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BMC
2020-03-01
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| סדרה: | Cell & Bioscience |
| נושאים: | |
| גישה מקוונת: | http://link.springer.com/article/10.1186/s13578-020-00387-2 |
| תגים: |
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