Canine non-B, non-T NK lymphocytes have a potential antibody-dependent cellular cytotoxicity function against antibody-coated tumor cells

Abstract Background The antibody-dependent cellular cytotoxicity (ADCC) is a cell-mediated immune defense mechanism in which effector immune cells actively lyse antibody-coated target cells. The ADCC of tumor cells is employed in the treatment of various cancers overexpressing unique antigens, and o...

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Detalhes bibliográficos

Principais autores:	Yoseop Kim, Soo-Hyeon Lee, Cheol-Jung Kim, Je-Jung Lee, Dohyeon Yu, Soomin Ahn, Dong-Jun Shin, Sang-Ki Kim
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2019-10-01
coleção:	BMC Veterinary Research
Assuntos:	Natural killer cells Canine Antibody-dependent cellular cytotoxicity Trastuzumab Cetuximab
Acesso em linha:	http://link.springer.com/article/10.1186/s12917-019-2068-5
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