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Concordance of MERFISH spatial transcriptomics with bulk and single-cell RNA sequencing

Single-cell RNA-seq is an important technology for capturing gene expression in individual cells. It has limitations as spatial context and accurate representation of cell types in the tissue are lost. Here, we show that MERFISH is comparable to scRNA-seq. Spatial transcriptomics extends single-cell...

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Principais autores: Jonathan Liu, Vanessa Tran, Venkata Naga Pranathi Vemuri, Ashley Byrne, Michael Borja, Yang Joon Kim, Snigdha Agarwal, Ruofan Wang, Kyle Awayan, Abhishek Murti, Aris Taychameekiatchai, Bruce Wang, George Emanuel, Jiang He, John Haliburton, Angela Oliveira Pisco, Norma F Neff
Format: Artigo
Jezik:Inglês
Izdano: Life Science Alliance LLC 2023-01-01
Serija:Life Science Alliance
Online dostop:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202201701
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