Bladder cancer-associated cancer-testis antigen-derived long peptides encompassing both CTL and promiscuous HLA class II-restricted Th cell epitopes induced CD4+ T cells expressing converged T-cell receptor genes in vitro

DEP domain containing 1 (DEPDC1) and M-phase phosphoprotein 1 (MPHOSPH1) are human cancer testis antigens that are frequently overexpressed in urinary bladder cancer. In a phase I/II clinical trial, a DEPDC1- and MPHOSPH1-derived short peptide vaccine demonstrated promising efficacy in preventing bl...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Miki Tsuruta, Shohei Ueda, Poh Yin Yew, Isao Fukuda, Sachiko Yoshimura, Hiroyuki Kishi, Hiroshi Hamana, Masatoshi Hirayama, Junji Yatsuda, Atsushi Irie, Satoru Senju, Eiji Yuba, Tomomi Kamba, Masatoshi Eto, Hideki Nakayama, Yasuharu Nishimura
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis Group 2018-04-01
Edice:	OncoImmunology
Témata:	bladder cancer cross presentation cancer-testis antigen dep domain containing 1 helper t-cell epitope m-phase phosphoprotein 1 t-cell receptor cancer immunotherapy tumor immunity
On-line přístup:	http://dx.doi.org/10.1080/2162402X.2017.1415687
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!