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Plasma Membrane Ca2+ ATPase Activity Enables Sustained Store-operated Ca2+ Entry in the Absence of a Bulk Cytosolic Ca2+ Rise

Abstract In many cell types, the rise in cytosolic Ca2+ due to opening of Ca2+ release-activated Ca2+ (CRAC) channels drives a plethora of responses, including secretion, motility, energy production, and gene expression. The amplitude and time course of the cytosolic Ca2+ rise is shaped by the rates...

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Principais autores: Pradeep Barak, Suneet Kaur, Erica Scappini, Charles J Tucker, Anant B Parekh
פורמט: Artigo
שפה:Inglês
יצא לאור: American Physiological Society 2022-01-01
סדרה:Function
נושאים:
Ca2+
plasma membrane ATPase
calcium channel
Transcription factor
גישה מקוונת:https://journals.physiology.org/doi/10.1093/function/zqac040
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