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Interferon-γ induced nitric oxide mediates in vitro neuronal damage by Trypanosoma cruzi-infected macrophages

Neuronal lesions and peripheral denervation in Chagas' disease are related to local inflammation; however, the pathogenic mechanisms of neuronal lesions in the heart and megavisceras are still unclear. We investigated the involvement of nitric oxide (NO) on neuronal lesion in co-cultures of neurons...

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Principais autores: Camila Megale de Almeida-Leite, Lúcia Maria da Cunha Galvão, Luis C.C. Afonso, Fernando de Queiróz Cunha, Rosa Maria Esteves Arantes
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2007-01-01
Serier:Neurobiology of Disease
Fag:
SCG
Co-cultures
T. cruzi
Nitric oxide
Neuron
IFN-γ
Online adgang:http://www.sciencedirect.com/science/article/pii/S0969996106002233
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