Reversible translocation of acyl-CoA:cholesterol acyltransferase (ACAT) between the endoplasmic reticulum and vesicular structures

The enzyme acyl-CoA:cholesterol acyltransferase (ACAT) is normally localized in the endoplasmic reticulum (ER) where it can esterify cholesterol for storage in lipid droplets and/or the formation of lipoproteins. Here, we report that ACAT can translocate from the ER into vesicular structures in resp...

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Detalhes bibliográficos

Principais autores:	Andrea Schiffmann, Lena Ahlswede, Gerald Gimpl
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-11-01
coleção:	Frontiers in Molecular Biosciences
Assuntos:	acyl-CoA:cholesterol acyltransferase (ACAT) bovine serum albumin (BSA) cycloheximide (CHX) disuccinimidyl suberate (DSS) cholesterol ester (CE) dansyl-cholestanol (DChol)
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fmolb.2023.1258799/full
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