Granulocyte colony-stimulating factor-induced hypersensitivity reaction with leukocytosis in a pediatric germ cell tumor patient: a case report

BackgroundChemotherapy-induced bone marrow suppression significantly increases the risk of febrile neutropenia (FN) in cancer patients. Granulocyte colony-stimulating factor (G-CSF) is a cornerstone therapy for FN prophylaxis and treatment that promotes myeloid progenitor cell proliferation and diff...

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Principais autores:	Yuhui Tan, Chaoyong Wei, Wenyan Xiao, Yilan Fu, Xi Chen, Yanxiang Tang, Changli Tang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-06-01
Colecção:	Frontiers in Pediatrics
Assuntos:	child efbemalenograstim alfa-vuxw febrile neutropenia filgrastim biosimilar granulocyte colony-stimulating factor hypersensitivity
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fped.2026.1749442/full
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