IgM-enriched immunoglobulins (Pentaglobin) may improve the microcirculation in sepsis: a pilot randomized trial

Abstract Background Polyclonal or IgM-enriched immunoglobulins may be beneficial during sepsis as an adjuvant immunomodulatory therapy. We aimed to test whether the infusion of IgM-enriched immunoglobulins improves microvascular perfusion during sepsis. Methods Single-centre, randomized, double-blin...

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Bibliographic Details

Main Authors:	Roberta Domizi, Erica Adrario, Elisa Damiani, Claudia Scorcella, Andrea Carsetti, Paolo Giaccaglia, Erika Casarotta, Vincenzo Gabbanelli, Simona Pantanetti, Elena Lamura, Silvia Ciucani, Abele Donati
Format:	Artigo
Language:	Inglês
Published:	Elsevier 2019-12-01
Series:	Annals of Intensive Care
Subjects:	Immunoglobulins Pentaglobin Sepsis Microcirculation Immunomodulation
Online Access:	https://doi.org/10.1186/s13613-019-0609-5
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