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KRAS/NRAS/BRAF Mutations as Potential Targets in Multiple Myeloma

In multiple myeloma the mutational profile is mainly represented by translocations involving chromosome 14 and by single nucleotide mutations, frequently involving genes implicated in the mitogen activated protein kinase (MAPK) pathway, as KRAS, NRAS, and, less frequently, BRAF. Because KRAS/NRAS/BR...

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Bibliografische gegevens
Hoofdauteurs: Sergiu Pasca, Ciprian Tomuleasa, Patric Teodorescu, Gabriel Ghiaur, Delia Dima, Vlad Moisoiu, Cristian Berce, Cristina Stefan, Aaron Ciechanover, Herman Einsele
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2019-10-01
Reeks:Frontiers in Oncology
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Online toegang:https://www.frontiersin.org/article/10.3389/fonc.2019.01137/full
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