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KRAS, NRAS, BRAF, HER2 and microsatellite instability in metastatic colorectal cancer – practical implications for the clinician

Colorectal cancer is a successful model of genetic biomarker development in oncology. Currently, several predictive or prognostic genetic alterations have been identified and are used in clinical practice. The RAS gene family, which includes KRAS and NRAS act as predictors for anti-epithelial growth...

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Principais autores: Afrăsânie Vlad-Adrian, Marinca Mihai Vasile, Alexa-Stratulat Teodora, Gafton Bogdan, Păduraru Marius, Adavidoaiei Anca Maria, Miron Lucian, Rusu Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: Sciendo 2019-09-01
coleção:Radiology and Oncology
Assuntos:
metastatic colorectal cancer
kras
nras
braf
her2
microsatellite instability
Acesso em linha:https://doi.org/10.2478/raon-2019-0033
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