Muscle progenitor cells are required for skeletal muscle regeneration and prevention of adipogenesis after limb ischemia

Skeletal muscle injury in peripheral artery disease (PAD) has been attributed to vascular insufficiency, however evidence has demonstrated that muscle cell responses play a role in determining outcomes in limb ischemia. Here, we demonstrate that genetic ablation of Pax7+ muscle progenitor cells (MPC...

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Библиографические подробности

Главные авторы:	Hasan Abbas, Lindsey A. Olivere, Michael E. Padgett, Cameron A. Schmidt, Brian F. Gilmore, Timothy J. McCord, Kevin W. Southerland, Joseph M. McClung, Christopher D. Kontos
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2023-03-01
Серии:	Frontiers in Cardiovascular Medicine
Предметы:	peripheral artery disease critical limb threatening ischemia muscle progenitor cells skeletal muscle regeneration fibro/adipogenic progenitor cells hind limb ischemia
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fcvm.2023.1118738/full
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