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Construction and application of a CRISPR/Cas9-assisted genomic editing system for Corynebacterium glutamicum

Abstract Corynebacterium glutamicum is widely used as microbial cell factory for various bioproducts, but its genomic editing efficiency needs to be improved. In this study, a highly efficient CRISPR/Cas9-assisted genomic editing system for C. glutamicum was constructed. This system mainly involves...

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Principais autores: Chengzhen Yao, Xiaoqing Hu, Xiaoyuan Wang
Formato: Artigo
Idioma:Inglês
Publicado em: SpringerOpen 2021-05-01
coleção:AMB Express
Assuntos:
Corynebacterium glutamicum
CRISPR/Cas9
Metabolic engineering
Genomic editing
l-Glutamic acid fermentation
Acesso em linha:https://doi.org/10.1186/s13568-021-01231-7
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