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Mannose-Coated Reconstituted Lipoprotein Nanoparticles for the Targeting of Tumor-Associated Macrophages: Optimization, Characterization, and In Vitro Evaluation of Effectiveness

Reconstituted high-density lipoprotein nanoparticles (rHDL NPs) have been utilized as delivery vehicles to a variety of targets, including cancer cells. However, the modification of rHDL NPs for the targeting of the pro-tumoral tumor-associated macrophages (TAMs) remains largely unexplored. The pres...

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Autores principales: Akpedje S. Dossou, Morgan E. Mantsch, Ammar Kapic, William L. Burnett, Nirupama Sabnis, Jeffery L. Coffer, Rance E. Berg, Rafal Fudala, Andras G. Lacko
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2023-06-01
Colección:Pharmaceutics
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Acceso en línea:https://www.mdpi.com/1999-4923/15/6/1685
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