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Hypertrophic Cardiomyopathy Mutations of Troponin Reveal Details of Striated Muscle Regulation

Striated muscle contraction is inhibited by the actin associated proteins tropomyosin, troponin T, troponin I and troponin C. Binding of Ca2+ to troponin C relieves this inhibition by changing contacts among the regulatory components and ultimately repositioning tropomyosin on the actin filament cre...

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Hlavní autoři: J. M. Chalovich, L. Zhu, D. Johnson
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-05-01
Edice:Frontiers in Physiology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fphys.2022.902079/full
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