QbD-engineered development and in vivo evaluation of an Articaine-loaded nanostructured lipid carrier in situ gel: A painless drug delivery platform for sustained periodontal anesthesia
Background: Achieving long-lasting topical anesthesia remains challenging in periodontal therapy. This study aimed to design and optimize articaine-loaded nanostructured lipid carriers (ART-NLCs) for sustained periodontal anesthesia. Methods: The NLCs were prepared using an emulsion evaporation tech...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier
2026-06-01
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| Series: | Next Nanotechnology |
| Assuntos: | |
| Acceso en liña: | http://www.sciencedirect.com/science/article/pii/S2949829526000653 |
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