Spirostan and spirosol saponin derivatives from Solanum muricatum Aiton and their cytotoxic activities: insights into bioactive compounds and molecular mechanisms

Abstract Solanum muricatum Aiton (Family: Solanaceae), commonly known as pepino, is a traditionally used edible plant with reported medicinal properties, though its bioactive compounds remain largely unexplored. This study aimed to isolate cytotoxic constituents from its aerial parts and investigate...

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Autors principals:	Fathy A. Behery, Mohamed A. M. El Gendy, Mohamed A. Zarka, Mubarak A. Alzubaidi, Hesham A. Abou-Zied, Gerhard Bringmann, Usama R. Abdelmohsen, Abeer H. Elmaidomy
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2025-09-01
Col·lecció:	Scientific Reports
Matèries:	Solanum muricatum Spirostan Spirosol saponins HepG2 A549 Molecular docking
Accés en línia:	https://doi.org/10.1038/s41598-025-03891-y
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