HDX-MS reveals nucleotide-dependent, anti-correlated opening and closure of SecA and SecY channels of the bacterial translocon

The bacterial Sec translocon is a multi-protein complex responsible for translocating diverse proteins across the plasma membrane. For post-translational protein translocation, the Sec-channel – SecYEG – associates with the motor protein SecA to mediate the ATP-dependent transport of pre-proteins ac...

Descripció completa

Dades bibliogràfiques

Autors principals:	Zainab Ahdash, Euan Pyle, William John Allen, Robin A Corey, Ian Collinson, Argyris Politis
Format:	Artigo
Idioma:	Inglês
Publicat:	eLife Sciences Publications Ltd 2019-07-01
Col·lecció:	eLife
Matèries:	hydrogen-deuterium exchange mass spectromtery conformational dynamics SecA SecYEG protein translocation
Accés en línia:	https://elifesciences.org/articles/47402
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!