Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth

Summary Target of rapamycin complex 1 (TORC1), which controls growth in response to nutrients, promotes ageing in multiple organisms. The fission yeast Schizosaccharomyces pombe emerges as a valuable genetic model system to study TORC1 function and cellular ageing. Here we exploited the combinatoria...

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Главные авторы:	Charalampos Rallis, Luis López-Maury, Teodora Georgescu, Vera Pancaldi, Jürg Bähler
Формат:	Artigo
Язык:	Inglês
Опубликовано:	The Company of Biologists 2014-01-01
Серии:	Biology Open
Предметы:	TOR S. pombe Cell growth Chronological lifespan Oxidative stress S6 kinase Sck2 Protein translation
Online-ссылка:	http://bio.biologists.org/content/3/2/161
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