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An in vivo evaluation of the antifibrotic potential of inulin against bile duct ligation-induced liver fibrosis

Objective(s): Hepatic fibrosis is a major cause of liver-related mortality worldwide. This study evaluated the hepatoprotective and antifibrotic effects of inulin, a natural polysaccharide, in a rat model of cholestasis induced by bile duct ligation (BDL).Materials and Methods: Thirty male Wistar ra...

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Principais autores: Yasaman Habibian-Fard, Mahsa Ale-Ebrahim, Parvaneh Mohseni-Moghaddam, Shadi Sarahroodi, Pejman Mortazavi
Format: Artigo
Sprog:Inglês
Udgivet: Mashhad University of Medical Sciences 2026-02-01
Serier:Iranian Journal of Basic Medical Sciences
Fag:
α-actins smooth muscle
anti-oxidants
bile duct ligation
cholestasis
farnesoid x receptor
factor-β1
inulin
liver fibrosis
transforming growth
Online adgang:https://ijbms.mums.ac.ir/article_27299_6f91640d30ce55a48f063727ce08dc99.pdf
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