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ASCT2 is a major contributor to serine uptake in cancer cells

Summary: The non-essential amino acid serine is a critical nutrient for cancer cells due to its diverse biosynthetic functions. While some tumors can synthesize serine de novo, others are auxotrophic and therefore reliant on serine uptake. Importantly, despite several transporters being known to be...

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Detalles Bibliográficos
Principais autores: Kelly O. Conger, Christopher Chidley, Mete Emir Ozgurses, Huiping Zhao, Yumi Kim, Svetlana E. Semina, Philippa Burns, Vipin Rawat, Lina Lietuvninkas, Ryan Sheldon, Issam Ben-Sahra, Jonna Frasor, Peter K. Sorger, Gina M. DeNicola, Jonathan L. Coloff
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2024-08-01
Series:Cell Reports
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Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2211124724008817
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