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Use of patient‐derived tumor organoid platform to predict the benefit of postoperative adjuvant chemotherapy for poor responders to neoadjuvant chemoradiotherapy in locally advanced rectal cancer

Abstract Postoperative adjuvant chemotherapy (AC) for poor responders to neoadjuvant chemoradiotherapy (nCRT) remains debatable among patients with locally advanced rectal cancer (LARC), necessitating biomarkers to accurately predict the benefits of AC. This study aimed to develop a patient‐derived...

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Principais autores: Weisong Xue, Ting Wang, Jiaxin Yao, Wei Wu, Dexin Chen, Botao Yan, Xiaoyu Dong, Yuting Tang, Yunli Zeng, Yueyu He, Peihua Cao, Fangyuan Shao, Wenhua Huang, Chuxia Deng, Jun Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2023-11-01
coleção:Bioengineering & Translational Medicine
Assuntos:
adjuvant chemotherapy
neoadjuvant chemoradiotherapy
nomogram
organoid
rectal cancer
Acesso em linha:https://doi.org/10.1002/btm2.10586
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