Transcription initiation at a consensus bacterial promoter proceeds via a ‘bind-unwind-load-and-lock’ mechanism

Transcription initiation starts with unwinding of promoter DNA by RNA polymerase (RNAP) to form a catalytically competent RNAP-promoter complex (RPo). Despite extensive study, the mechanism of promoter unwinding has remained unclear, in part due to the transient nature of intermediates on path to RP...

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Hlavní autoři:	Abhishek Mazumder, Richard H Ebright, Achillefs N Kapanidis
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	eLife Sciences Publications Ltd 2021-10-01
Edice:	eLife
Témata:	RNA polymerase smFRET transcription initiation
On-line přístup:	https://elifesciences.org/articles/70090
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