Characterization and impact of non‐canonical WNT signaling on outcomes of urothelial carcinoma

Abstract Background Non‐canonical WNT family (WNT5A pathway) signaling via WNT5A through ROR1 and its partner, ROR2, or Frizzled2 (FZD2) is linked to processes driving tumorigenesis and therapy resistance. We utilized a large dataset of urothelial carcinoma (UC) tumors to characterize non‐canonical...

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Hauptverfasser:	Margaret Meagher, Harris Krause, Andrew Elliott, Alex Farrell, Emmanuel S. Antonarakis, Bruno Bastos, Elisabeth I. Heath, Christina Jamieson, Tyler F. Stewart, Aditya Bagrodia, Chadi Nabhan, Matt Oberley, Rana R. McKay, Amirali Salmasi
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2024-04-01
Schriftenreihe:	Cancer Medicine
Schlagworte:	FZD2 Non‐canonical ROR Urothelial carcinoma WNT signaling WNT5A
Online-Zugang:	https://doi.org/10.1002/cam4.7148
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