Matrix Remodeling and Hyaluronan Production by Myofibroblasts and Cancer-Associated Fibroblasts in 3D Collagen Matrices

The tumor microenvironment is a key modulator in cancer progression and has become a novel target in cancer therapy. An increase in hyaluronan (HA) accumulation and metabolism can be found in advancing tumor progression and are often associated with aggressive malignancy, drug resistance and poor pr...

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Bibliografische gegevens

Hoofdauteurs:	Jiranuwat Sapudom, Claudia Damaris Müller, Khiet-Tam Nguyen, Steve Martin, Ulf Anderegg, Tilo Pompe
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	MDPI AG 2020-09-01
Reeks:	Gels
Onderwerpen:	hyaluronan tumor microenvironment transforming growth factor beta 1 matrix remodeling myofibroblast cancer associated fibroblast
Online toegang:	https://www.mdpi.com/2310-2861/6/4/33
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