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Functional Requirements for Heparan Sulfate Biosynthesis in Morphogenesis and Nervous System Development in C. elegans.

The regulation of cell migration is essential to animal development and physiology. Heparan sulfate proteoglycans shape the interactions of morphogens and guidance cues with their respective receptors to elicit appropriate cellular responses. Heparan sulfate proteoglycans consist of a protein core w...

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Autors principals: Cassandra R Blanchette, Andrea Thackeray, Paola N Perrat, Siegfried Hekimi, Claire Y Bénard
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2017-01-01
Col·lecció:PLoS Genetics
Accés en línia:https://doi.org/10.1371/journal.pgen.1006525
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