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Induction of humoral and cell-mediated immunity to the NS1 protein of TBEV with recombinant Influenza virus and MVA affords partial protection against lethal TBEV infection in mice

IntroductionTick-borne encephalitis virus (TBEV) is one of the most relevant tick-transmitted neurotropic arboviruses in Europe and Asia and the causative agent of tick-borne encephalitis (TBE). Annually more than 10,000 TBE cases are reported despite having vaccines available. In Europe, the vaccin...

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Principais autores: Jana Beicht, Mareike Kubinski, Isabel Zdora, Christina Puff, Jeannine Biermann, Thomas Gerlach, Wolfgang Baumgärtner, Gerd Sutter, Albert D. M. E. Osterhaus, Chittappen Kandiyil Prajeeth, Guus F. Rimmelzwaan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-07-01
coleção:Frontiers in Immunology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1177324/full
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