Germ cells are essential for testicular morphogenesis and functional reconstruction in a porcine xenograft model

Abstract Reconstruction of functional testis tissue can provide new opportunities for in vitro spermatogenesis and fertility restoration in livestock. Although testis reconstruction has been reported in several species, the germ cell dependent mechanisms underlying de novo testicular morphogenesis r...

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Bibliografische Detailangaben

Hauptverfasser:	Min-Gi Han, Yoseop Jeon, Hyoyoung Maeng, Donghyeon Kim, Jeong Tae Do, Kwonho Hong, Youngsok Choi, Hyuk Song
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2026-03-01
Schriftenreihe:	Scientific Reports
Schlagworte:	Xenograft Testicular morphogenesis Spermatogonial stem cells Testis reconstruction Porcine testis
Online-Zugang:	https://doi.org/10.1038/s41598-026-44916-4
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